AKTIVITAS ANTI NYAMUK MIKROKAPSUL MINYAK ASIRI Citrus aurantifolia TERHADAP Aedes aegypti
Abstract
Pada penelitian ini, telah dilakukan evaluasi sifat antinyamuk dari mikrokapsul yang berisi minyak asiri kulit jeruk nipis (Citrus aurantifolia) terhadap nyamuk Aedes aegypti. Preparasi minyak asiri dilakukan dengan metode hidrodistilasi; pembuatan mikrokapsul dengan metode koaservasi kompleks menggunakan penyalut alginat-gelatin, pengikat silang glutaraldehid, dan pengemulsi span-80 dan tween-80; pelepasan minyak asiri dalam mikrokapsul dilakukan dengan rangsangan magnetic stirrer 100 rpm; dan uji aktivitas antinyamuk dilakukan terhadap nyamuk A. aegypti. Hasil preparasi minyak asiri diperoleh rendemen sebesar 0,44%, dengan kualitas baik, berwarna kuning pucat dengan aroma segar khas jeruk nipis, komponen utama minyak asiri d-limonen (33,14%) dan b-pinen (28,32%). Mikrokapsul diperoleh dengan rendemen sebesar 47,3%, oil content sebesar 66,7%, dan efisiensi enkapsulasi sebesar 87,9%. Rata-rata pelepasan minyak asiri dari mikrokapsul dari hari pertama hingga hari ketujuh berkisar 44,7-65,9%. Nilai % total perlindungan dari minyak asiri C. aurantifolia utuh lebih tinggi daripada limonen dan mikrokapsul, hal ini menunjukkan ada kerja sinergis antara komponen-komponen yang terdapat dalam minyak asiri. Rentang total perlindungan terhadap nyamuk A. aegypti antara 85,0-98,8%.
Keywords
Full Text:
PDFReferences
Bhatt, S., Gething, P.W., Brady, O.J., Messina,
J.P., Farlow, A. W., Moyes, C.L., Drake, J.M.,
Brownstein, J.S., Hoen, A.G., Sankoh, O.,
Myers, M. F., George, D. B., Jaenisch, T.,
William Wint, G. R., Simmons, C.P., Scott,
T.W., Farrar, J.J., & Hay, S. I. The global
distribution and burden of dengue. Nature.
(7446), 504-507 (2013).
Lin, L.Y., Chuang, C.H., & Yang, K.M. Lime
(Citrus aurantifolia (Christm.) swingle)
essential oils: Volatile compounds, antioxidant
capacity, and hypolipidemic effect. Foods. 8(9)
(2019).
Sotelo-Boyás, M.E., Correa-Pacheco, Z.N.,
Bautista-Baños, S., & Corona-Rangel, M.L.
Physicochemical characterization of chitosan
nanoparticles and nanocapsules incorporated
with lime essential oil and their antibacterial
activity against food-borne pathogens. LWT -
Food Science and Technology. 77, 15–20
(2017).
Aripin, D., Julaeha, E., Dardjan, M., &
Cahyanto, A. Chemical composition of Citrus
spp. and oral antimicrobial effect of Citrus spp.
peels essential oils against Streptococcus
mutans. Padjadjaran Journal of Dentistry.
(1), 1–11 (2015).
Soonwera, M. Efficacy of Essential Oils from
Citrus plants against Mosquito Vectors Aedes
aegypti (Linn.) and Culex quinquefasciatus
(Say). 11,669-681 (2015).
Hamid, H. A., N. Silvarajoo, and N. A. Hamid.
Chemical Composition and Repellent Activity
Against Mosquito Aedes Aegypti of
Pelargonium radula, Syzygium aromaticum
and Citrus aurantifolia Essential Oils:
Materials Science Forum. 981: 253- 257
(2020).
Aziz, Z.A.A., Ahmad, A., Setapar, S.H.M.,
Karakucuk, A., Azim, M.M., Lokhat, D.,
Rafatullah, M., Ganash, M., Kamal, M.A., &
Ashraf, G.M. Essential Oils: Extraction
Techniques, Pharmaceutical And Therapeutic
Potential - A Review. Current Drug
Metabolism. 19(13), 1100–1110 (2018).
Astuti, E., Sunarminingsih, R., Jenie, U.A.,
Mubarika, S., & Sismindari. Pengaruh Lokasi
Tumbuh, Umur Tanaman, dan Variasi Jenis
Destilasi terhadap Komposisi Senyawa Minyak
Atsiri Rimpang Curcuma mangga Produksi
beberapa Sentra di Yogyakarta. Jurnal
Manusia dan Tumbuhan. 21(3), 2–7 (2014).
Rattanawongwiboon, T., Hemvichian, K.,
Lertsarawut, P., & Suwanmala, P. Chitosanpoly(ethylene glycol) diacrylate beads prepared
by radiation-induced crosslinking and their
promising applications derived from
encapsulation of essential oils. Radiation
Physics and Chemistry. 170, 108656 (2020)
Wahyudi, T., Mulyawan, A.S., Kasipah, C.,
Prayudie, U., & Julaeha, E. Pembuatan
Mikrokapsul Minyak Jeruk (Citrus aurantifolia)
Untuk Aplikasi Pada Penyempurnaan Tekstil.
Arena Tekstil. 32(1), 1–8 (2017).
Julaeha, E., Nugeraha, R., Nurzaman, M.,
Kurnia, D., Wahyudi, T., & Rosandi, Y.
Characterization of ethyl cellulose (EC)
microcapsules for lime oil encapsulation.
Journal of Physics: Conference Series. 1080(1)
(2018).
Puspita, S., Eddy, D.R., Wahyudi, T., &
Julaeha, E. Microencapsulation of Lime Peel
Essential Oils (Citrus aurantifolia) with
Complex Coacervation Methods using
Gelatin/Sodium Alginate Coating. Revista de
Chimie. 71(12), 146-155 (2020).
Julaeha, E., Nurzaman, M., Eddy, D.R.,
Kurnia, D., Puspita, S., Rosandi, Y., Wahyudi,
T., & Al Anshori, J. Microencapsulation of
lime (Citrus aurantifolia) oil for antibacterial
finishing of cotton fabric. RSC Advances.
(3), 1743-1749 (2021).
Solomon, B., Sahle, F.F., Gebre-Mariam, T.,
Asres, K. & Neubert, R. H. H.
Microencapsulation of citronella oil for
mosquito-repellent application: Formulation
and in vitro permeation studies. Eur. J. Pharm.
Biopharm. 80, 61–66 (2012).
Grancaric, A.M., Laird, K., Botteri, L., Shen, J.
& Laatikainen, K. Microencapsulation for
improved mosquitoes’ repellent efficacy of
cotton fabrics. IOP Conf. Ser. Mater. Sci. Eng.
, 18–23 (2020).
Chung, S.K., Seo, J.Y., Lim, J.H., Park, H.H.,
Yea, M.J., & Park, H.J. Microencapsulation of
essential oil for insect repellent in food
packaging system. Journal of Food Science.
(5), 1–6 (2013).
Dinarvand, R., Moghadam, S. H., Sheikhi, A.,
& Atyabi, F. Effect Of Surfactant HLB And
Different Formulation Variables On The
Properties Of Poly-D,L-Lactide Microspheres
Of Naltrexone Prepared By Double Emulsion
Technique. Journal of Microencapsulation.
(2): 139–151 (2005).
Maji, T.K., Baruah, I., Dube, S., & Hussain,
M.R. Microencapsulation of Zanthoxylum
limonella oil (ZLO) in glutaraldehyde
crosslinked gelatin for mosquito repellent
application. Bioresource Technology. 98(4),
–844 (2007).
Misni, N., Nor, Z.M., & Ahmad, R. Repellent
effect of microencapsulated essential oil in
lotion formulation against mosquito bites.
Journal of Vector Borne Diseases. 54(1), 44–
(2017).
Mahato, N., Sinha, M., Sharma, K.,
Koteswararao, R. & Cho, M. H. Modern
extraction and purification techniques for
obtaining high purity food-grade bioactive
compouds and value-addes co-products from
citrus wastes. Foods vol. 8 (2019)
Silvestre, W.P., Livinalli, N.F., Baldasso, C., &
Tessaro, I.C. Pervaporation in the separation of
essential oil components: A review. Trends in
Food Science and Technology. 93(September),
–52 (2019).
Raut, J.S. & Karuppayil, S.M. A status review
on the medicinal properties of essential oils.
Industrial Crops and Products. 62, 250–264
(2014).
Timilsena, Y.P., Akanbi, T.O., Khalid, N.,
Adhikari, B., & Barrow, C.J. Complex
coacervation: Principles, mechanisms and
applications in microencapsulation.
International Journal of Biological
Macromolecules. 121, 1276–1286 (2019).
Mollet, Hans; Grubenmann, A. 2 Emulsions -
Properties and Production (2001).
Li, Y., Jia, H., Cheng, Q., Pan, F., & Jiang, Z.
Sodium alginate – gelatin polyelectrolyte
complex membranes with both high water
vapor permeance and high permselectivity.
Journal of Membrane Science. 375(1–2), 304–
(2011).
Specos, M.M.M., García, J.J., Tornesello, J.,
Marino, P., Vecchia, D.M., Tesoriero, D.M.V.,
& Hermida, L.G. Microencapsulated citronella
oil for mosquito repellent finishing of cotton
textiles. Transactions of the Royal Society of
Tropical Medicine and Hygiene. 104(10), 653–
(2010).
DOI: http://dx.doi.org/10.31266/at.v36i2.7337
Refbacks
- There are currently no refbacks.
Arena Tekstil indexed by:
Copyright Arena Tekstil (E-ISSN: 2548-7264, P-ISSN: 0518-4010)
Published by: BALAI BESAR TEKSTIL, Jl. Jenderal Ahmad Yani No. 390, Bandung.
